Reserve concomitant prescribing of benzodiazepines or other CNS depressants in patients in methadone treatment method to those for whom alternatives to benzodiazepines or other CNS depressants are inadequate.Supportive care is usually furnished for neonates with milder situations. Pharmacologic intervention is carried out when moderate to significa
The concomitant utilization of METHADOSE with all cytochrome P450 3A4, 2B6, 2C19, 2C9 or 2D6 inhibitors could lead to a rise in methadone plasma concentrations, which could induce most likely fatal respiratory despair. Moreover, discontinuation of concomitantly made use of cytochrome P450 3A4, 2B6, 2C19, or 2C9 inducers may also bring about a rise
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